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Bone Marrow Transplantation

BONE MARROW TRANSPLANT

A bone marrow transplant is done to replace damaged bone marrow that may have been caused due to disease, infection or chemotherapy. Here, blood stem cells are transplanted which travel to the bone marrow where they promote the growth of new bone marrow by producing new blood cells. Bone marrow is responsible to create red blood cells, white blood cells, platelets, etc.

Causes of damaged Bone Marrow:

  • Aplastic anemia where the bone marrow stops making new blood cells
  • Leukemia, Lymphoma and Multiple myelomas
  • Damaged bone marrow from chemotherapy
  • Congenital Neutropenia is a disorder causing recurring infections
  • Sickle cell anemia
  • Thalassemia

Types of Bone Marrow Transplant

Autologous Transplants: This procedure involves the use of a person’s own stem cells, wherein, the cells are harvested, frozen and stored, then infused back into the patient after intensive therapy. Once the treatment is completed, the cells are returned to the body. However, this technique is rarely used but reduces some serious complications.

The procedure typically takes about an hour. The stem cells after entering the bloodstream, travel to the bone marrow and begin to produce new blood cells, and this process is referred to as ‘Engraftment’.

Using cells from the person’s own body during your stem cell transplant offers advantages over receiving stem cells from a donor such as cases of incompatibility between the donor's cells and recipient’s cells do not occur in cases of an autologous stem cell transplant.

Why You May Need An Autologous Transplant?

An autologous stem cell transplant is used to treat the following disorders:

  • Hodgkin's lymphoma
  • Myeloma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders

Allogenic Transplants: This procedure involves the usage of cells from a donor and here the donor must be a close genetic match to the recipient. In fact, the success rate is dependent on how close the match is.

An Allogenic stem cell transplant uses healthy blood stem cells from a donor to replace the diseased and damaged bone marrow.  A donor may be a family member, an acquaintance or someone who is unrelated. The stem cells, in this case, can be collected from the donor's blood or bone marrow within a donor's hipbone as well as from a donated umbilical cord.

Here it is important to note that before undergoing an Allogenic stem cell transplant, a high dosage of chemotherapy or radiation is incorporated to destroy the diseased cells and prepare the body for the donor cells.

Why You May Need An Allogenic Transplant?

An allogeneic stem cell transplant is used to treat the following disorders:

  • Acute leukemia
  • Adrenoleukodystrophy
  • Aplastic anemia
  • Bone marrow failure syndromes
  • Chronic leukemia
  • Hemoglobinopathies
  • Hodgkin's lymphoma
  • Immune deficiencies
  • Inborn errors of metabolism
  • Multiple myelomas
  • Myelodysplastic syndromes
  • Neuroblastoma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders
  • POEMS syndrome
  • Primary amyloidosis

Umbilical Cord Blood Transplants: Umbilical Cord contains the cord blood and placenta of a newborn child. It can be collected and frozen for later use. Cord blood contains hematopoietic stem which can produce different cells such as red blood cells, white blood cells, and platelets. They are responsible for maintaining blood production in the body and have been used for many years in bone marrow transplants to treat blood diseases such as Leukemia.

Cord blood cells are also immunologically sound as they have not been exposed to infections. This makes them more tolerant against a tissue mismatch between the cord cells and the patient. Thus, they can be used to transplant patients who do not have a fully matched available donor as well.

Haploidentical Transplants: Haploidentical transplants can often be performed more than traditional unrelated donor transplants. Relatives may be eligible to make a donation on a short notice, which may be less likely for unrelated donors.

For donors and patients alike, the procedure for a Haploidentical transplant is much the same as for a standard Allogenic transplant. However, the main difference is that in this type of transplant, patients receive a high dosage of chemotherapy days after the transplant. Success rates for Haploidentical transplants are similar to those for conventional transplants.

Frequently Asked Questions

What is a bone marrow transplant?

Bone marrow transplant (BMT) is a procedure to treat certain cancers and various diseases of blood and bone marrow.

What does it involve?

BMT involves taking healthy bone marrow stem cells from a donor and placing them into a patient’s bloodstream.

Why would someone need a bone marrow transplant?

Bone marrow transplants help treat cancers and diseases of the blood and bone marrow by replacing unhealthy stem cells with healthy ones. It is also helpful for people whose bone marrow has been destroyed by chemotherapy or radiation treatment. It also treats diseases that cause a person’s bone marrow to stop functioning.

How long does it take to recover from a bone marrow transplant?

Every person’s situation is different but most people can expect to spend at least 30 days in the hospital when your body rebuilds the immune system. Once the immune system is strong enough the rest of the recovery can be continued at home. It can take several more months or even years after BMT for your immune function to fully recover.

Range of Treatment Cost

15000 - 35000 USD

Top Hospitals

Rating :

Bone Marrow Transplantation
Fortis Hospital - New Delhi

Fortis Hospital, Shalimar Bagh, New Delhi, is a multi super speciality hospital offering super specializations within departments, with the mission of providing quality medical care. This is one of the largest hospit.....

Rating :

NABHNABL

Bone Marrow Transplantation
Sarvodaya Hospital And Research Centre

Sarvodaya Hospital & Research Centre is amongst the finest medical institutions in Faridabad. Spread across 4.25 acres, the hospital has 300 Beds, 65 ICU Beds, 6 Operation Theatres, and a floor based Cath Lab. It delivers care-base.....

Rating :

NABHNABL

Bone Marrow Transplantation
Paras Health Care Pvt Ltd

Paras Hospitals, Gurgaon is the 250 bedded flag ship hospital of Paras Healthcare. It is a state of the art multi super specialty hospital providing a complete spectrum of advanced medical and surgical interventions with a comprehensive mix of inpatient and outpati.....

Rating :

NABHJCI

Bone Marrow Transplantation
Aster Medcity

Aster Medcity is a Quaternary care healthcare center in the south Indian city of Kochi and one of the largest in the state of Kerala. It is owned and managed by Aster DM Healthcare, a Dubai based healthcare conglomerate founded by Azad Moopen. This was the third ve.....

Rating :

NABHNABLJCI

Bone Marrow Transplantation
Fortis Escorts Heart Institute & Research Ltd

Fortis Escorts Heart Institute (FEHI), Delhi, a pioneer and centre of excellence in cardiac care, is recognised for its path-breaking work and service to the numerous heart patients, who have benefitted from treatment, at its facility. Armed with clinical expertise.....

Rating :

Bone Marrow Transplantation
International Fertility Centre

International Fertility Centre (IFC) is a network of 10+ IVF clinics located in India, Nepal and Afghanistan and has its headquarters in New Delhi. IFC is backed with India’s leading IVF specialist Dr. Rita Bakshi along with a solid team that is committed to .....

Rating :

NABH

Bone Marrow Transplantation
SHARP SIGHT

Established in 1998, Sharp Sight (Group of Eye Hospitals) is among the largest provider of quality eye care in Delhi-NCR. We take pride in offering the latest world-class technologies for eye care and ophthalmic treatments at very affordable cost. Our team of ophth.....

Rating :

NABHNABL

Bone Marrow Transplantation
SAKRA WORLD HOSPITAL

Sakra World Hospital is the coming together of Toyota Tsusho’s excellence in process driven systems and SECOM Hospital’s over 22 years of experience in running hospitals in Japan, across 18 hospitals with 5500 beds.Making Sakra World Hospital a very pro.....

Rating :

NABH

Bone Marrow Transplantation
Fortis Hospital, Noida

Fortis Hospital, Noida is a premier state-of-the-art facility with over 200 beds including 7 operation theatres. The hospital is positioned as a Centre of Excellence in oncology, orthopaedics, neuroscience, liver transplant, kidney transplant, and with a key focus .....

Rating :

NABHJCI

Bone Marrow Transplantation
Care Hospitals

The CARE Group’s flagship CARE Hospitals, located in Banjara Hills - a prime location in Hyderabad, was set up in the year 2000. Today, t.....

Top Doctors

Dr Dharma Choudhary
Dr Dharma Choudhary

India

Specialty - Bone Marrow Transplant

Dr Esha Kaul
Dr Esha Kaul

India

Specialty - Bone Marrow Transplant

 Dr Vivek Radhakrishnan
Dr Vivek Radhakrishnan

India

Specialty - Bone Marrow Transplant

Dr Subhaprakash   Sanyal
Dr Subhaprakash Sanyal

India

Specialty - Bone Marrow Transplant

Dr Vimal Kumar  G
Dr Vimal Kumar G

India

Specialty - Bone Marrow Transplant

Dr Vivek Goswami
Dr Vivek Goswami

India

Specialty - Bone Marrow Transplant

Patient Stories

  1. After a long endeavour, we gave birth to John, our beloved son. But destiny planned otherwise. He was an unhealthy child. After visiting many doctors, it was concluded that our son needs a BMT. We were scattered and confused. We didn’t have anyone to talk to or guide us. We were clueless. One day, my husband was surfing the net and came across Medtravels. We were confused but we had to take a chance. Hesitantly, we contacted their online chat and immediately after sharing our number an executive got in touch with me. We explained everything in details and also shared the reports on mail. Soon after, we received 5 quotes from the team from 5 different hospitals and with detailed profiles. It helped us develop a confidence and we decided to travel to India. Medtravels also helped us with affordable travel and accommodation plans which helped us to manage our expenses. Our son was treated with great care in the hospital and now he is slowly recovering. Medtravels and their hospital has helped giving our son a new life. We will be forever thankful to them.

Request A Quote

BONE MARROW TRANSPLANT

A bone marrow transplant is done to replace damaged bone marrow that may have been caused due to disease, infection or chemotherapy. Here, blood stem cells are transplanted which travel to the bone marrow where they promote the growth of new bone marrow by producing new blood cells. Bone marrow is responsible to create red blood cells, white blood cells, platelets, etc.

Causes of damaged Bone Marrow:

  • Aplastic anemia where the bone marrow stops making new blood cells
  • Leukemia, Lymphoma and Multiple myelomas
  • Damaged bone marrow from chemotherapy
  • Congenital Neutropenia is a disorder causing recurring infections
  • Sickle cell anemia
  • Thalassemia

Types of Bone Marrow Transplant

Autologous Transplants: This procedure involves the use of a person’s own stem cells, wherein, the cells are harvested, frozen and stored, then infused back into the patient after intensive therapy. Once the treatment is completed, the cells are returned to the body. However, this technique is rarely used but reduces some serious complications.

The procedure typically takes about an hour. The stem cells after entering the bloodstream, travel to the bone marrow and begin to produce new blood cells, and this process is referred to as ‘Engraftment’.

Using cells from the person’s own body during your stem cell transplant offers advantages over receiving stem cells from a donor such as cases of incompatibility between the donor's cells and recipient’s cells do not occur in cases of an autologous stem cell transplant.

Why You May Need An Autologous Transplant?

An autologous stem cell transplant is used to treat the following disorders:

  • Hodgkin's lymphoma
  • Myeloma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders

Allogenic Transplants: This procedure involves the usage of cells from a donor and here the donor must be a close genetic match to the recipient. In fact, the success rate is dependent on how close the match is.

An Allogenic stem cell transplant uses healthy blood stem cells from a donor to replace the diseased and damaged bone marrow.  A donor may be a family member, an acquaintance or someone who is unrelated. The stem cells, in this case, can be collected from the donor's blood or bone marrow within a donor's hipbone as well as from a donated umbilical cord.

Here it is important to note that before undergoing an Allogenic stem cell transplant, a high dosage of chemotherapy or radiation is incorporated to destroy the diseased cells and prepare the body for the donor cells.

Why You May Need An Allogenic Transplant?

An allogeneic stem cell transplant is used to treat the following disorders:

  • Acute leukemia
  • Adrenoleukodystrophy
  • Aplastic anemia
  • Bone marrow failure syndromes
  • Chronic leukemia
  • Hemoglobinopathies
  • Hodgkin's lymphoma
  • Immune deficiencies
  • Inborn errors of metabolism
  • Multiple myelomas
  • Myelodysplastic syndromes
  • Neuroblastoma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders
  • POEMS syndrome
  • Primary amyloidosis

Umbilical Cord Blood Transplants: Umbilical Cord contains the cord blood and placenta of a newborn child. It can be collected and frozen for later use. Cord blood contains hematopoietic stem which can produce different cells such as red blood cells, white blood cells, and platelets. They are responsible for maintaining blood production in the body and have been used for many years in bone marrow transplants to treat blood diseases such as Leukemia.

Cord blood cells are also immunologically sound as they have not been exposed to infections. This makes them more tolerant against a tissue mismatch between the cord cells and the patient. Thus, they can be used to transplant patients who do not have a fully matched available donor as well.

Haploidentical Transplants: Haploidentical transplants can often be performed more than traditional unrelated donor transplants. Relatives may be eligible to make a donation on a short notice, which may be less likely for unrelated donors.

For donors and patients alike, the procedure for a Haploidentical transplant is much the same as for a standard Allogenic transplant. However, the main difference is that in this type of transplant, patients receive a high dosage of chemotherapy days after the transplant. Success rates for Haploidentical transplants are similar to those for conventional transplants.

Frequently Asked Questions

What is a bone marrow transplant?

Bone marrow transplant (BMT) is a procedure to treat certain cancers and various diseases of blood and bone marrow.

What does it involve?

BMT involves taking healthy bone marrow stem cells from a donor and placing them into a patient’s bloodstream.

Why would someone need a bone marrow transplant?

Bone marrow transplants help treat cancers and diseases of the blood and bone marrow by replacing unhealthy stem cells with healthy ones. It is also helpful for people whose bone marrow has been destroyed by chemotherapy or radiation treatment. It also treats diseases that cause a person’s bone marrow to stop functioning.

How long does it take to recover from a bone marrow transplant?

Every person’s situation is different but most people can expect to spend at least 30 days in the hospital when your body rebuilds the immune system. Once the immune system is strong enough the rest of the recovery can be continued at home. It can take several more months or even years after BMT for your immune function to fully recover.

15000 - 35000 USD

Top Hospitals

Rating :

Thyroidectomy
Fortis Hospital - New Delhi

Fortis Hospital, Shalimar Bagh, New Delhi, is a multi super speciality hospital offering super specializations within departments, with the mission of providing quality medical care. This is one of the largest hospit.....

Rating :

NABHNABL

Bone Marrow Transplanation
Sarvodaya Hospital And Research Centre

Sarvodaya Hospital & Research Centre is amongst the finest medical institutions in Faridabad. Spread across 4.25 acres, the hospital has 300 Beds, 65 ICU Beds, 6 Operation Theatres, and a floor based Cath Lab. It delivers care-base.....

Rating :

NABHNABL

Angioplasty
Paras Health Care Pvt Ltd

Paras Hospitals, Gurgaon is the 250 bedded flag ship hospital of Paras Healthcare. It is a state of the art multi super specialty hospital providing a complete spectrum of advanced medical and surgical interventions with a comprehensive mix of inpatient and outpati.....

Rating :

NABHJCI

Bone Marrow Transplanation
Aster Medcity

Aster Medcity is a Quaternary care healthcare center in the south Indian city of Kochi and one of the largest in the state of Kerala. It is owned and managed by Aster DM Healthcare, a Dubai based healthcare conglomerate founded by Azad Moopen. This was the third ve.....

Rating :

NABHNABLJCI

Gastric Bypass Surgery
Fortis Escorts Heart Institute & Research Ltd

Fortis Escorts Heart Institute (FEHI), Delhi, a pioneer and centre of excellence in cardiac care, is recognised for its path-breaking work and service to the numerous heart patients, who have benefitted from treatment, at its facility. Armed with clinical expertise.....

Rating :

Hysteroscopy
International Fertility Centre

International Fertility Centre (IFC) is a network of 10+ IVF clinics located in India, Nepal and Afghanistan and has its headquarters in New Delhi. IFC is backed with India’s leading IVF specialist Dr. Rita Bakshi along with a solid team that is committed to .....

Rating :

NABH

Vitrectomy
SHARP SIGHT

Established in 1998, Sharp Sight (Group of Eye Hospitals) is among the largest provider of quality eye care in Delhi-NCR. We take pride in offering the latest world-class technologies for eye care and ophthalmic treatments at very affordable cost. Our team of ophth.....

Rating :

NABHNABL

Coronary Angiogram
SAKRA WORLD HOSPITAL

Sakra World Hospital is the coming together of Toyota Tsusho’s excellence in process driven systems and SECOM Hospital’s over 22 years of experience in running hospitals in Japan, across 18 hospitals with 5500 beds.Making Sakra World Hospital a very pro.....

Rating :

NABH

Avr/ Mvr
Fortis Hospital, Noida

Fortis Hospital, Noida is a premier state-of-the-art facility with over 200 beds including 7 operation theatres. The hospital is positioned as a Centre of Excellence in oncology, orthopaedics, neuroscience, liver transplant, kidney transplant, and with a key focus .....

Rating :

NABHJCI

Angiography
Care Hospitals

The CARE Group’s flagship CARE Hospitals, located in Banjara Hills - a prime location in Hyderabad, was set up in the year 2000. Today, t.....

Top Doctors

Dr Dharma Choudhary
Dr Dharma Choudhary

India

Specialty - Bone Marrow Transplant

Dr Esha Kaul
Dr Esha Kaul

India

Specialty - Bone Marrow Transplant

 Dr Vivek Radhakrishnan
Dr Vivek Radhakrishnan

India

Specialty - Bone Marrow Transplant

Dr Subhaprakash   Sanyal
Dr Subhaprakash Sanyal

India

Specialty - Bone Marrow Transplant

Dr Vimal Kumar  G
Dr Vimal Kumar G

India

Specialty - Bone Marrow Transplant

Dr Vivek Goswami
Dr Vivek Goswami

India

Specialty - Bone Marrow Transplant

Patient Stories

  1. After a long endeavour, we gave birth to John, our beloved son. But destiny planned otherwise. He was an unhealthy child. After visiting many doctors, it was concluded that our son needs a BMT. We were scattered and confused. We didn’t have anyone to talk to or guide us. We were clueless. One day, my husband was surfing the net and came across Medtravels. We were confused but we had to take a chance. Hesitantly, we contacted their online chat and immediately after sharing our number an executive got in touch with me. We explained everything in details and also shared the reports on mail. Soon after, we received 5 quotes from the team from 5 different hospitals and with detailed profiles. It helped us develop a confidence and we decided to travel to India. Medtravels also helped us with affordable travel and accommodation plans which helped us to manage our expenses. Our son was treated with great care in the hospital and now he is slowly recovering. Medtravels and their hospital has helped giving our son a new life. We will be forever thankful to them.

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