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Bone Marrow Transplantation

BONE MARROW TRANSPLANT

A bone marrow transplant is done to replace damaged bone marrow that may have been caused due to disease, infection or chemotherapy. Here, blood stem cells are transplanted which travel to the bone marrow where they promote growth of new bone marrow by producing new blood cells. Bone marrow is responsible to create red blood cells, white blood cells, platelets, etc.

 

Causes of damaged Bone Marrow:

  • Aplastic anemia where bone marrow stops making new blood cells
  • Leukemia, Lymphoma and Multiple myeloma
  • Damaged bone marrow from chemotherapy
  • Congenital Neutropenia is a disorder causing recurring infections
  • Sickle cell anemia
  • Thalassemia

Types of Bone Marrow Transplant

Autologous Transplants: This procedure involves the use of a person’s own stem cells, wherein, the cells are harvested, frozen and stored, then infused back into the patient after intensive therapy. Once the treatment is completed, the cells are returned to the body. However, this technique is rarely used but reduces some serious complications.

The procedure typically takes about an hour. The stem cells after entering the bloodstream, travel to the bone marrow and begin to produce new blood cells, and this process is referred to as ‘Engraftment’.

Using cells from the person’s own body during your stem cell transplant offers advantages over receiving stem cells from a donor such as cases of incompatibility between the donor's cells and recipient’s cells do not occur in cases of an autologous stem cell transplant.

 

Why You May Need An Autologous Transplant?

An autologous stem cell transplant is used to treat the following disorders:

  • Hodgkin's lymphoma
  • Myeloma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders

 

Allogenic Transplants: This procedure involves the usage of cells from a donor and here the donor must be a close genetic match to the recipient. Infact, the success rate is dependent on how close the match is.

An Allogenic stem cell transplant uses healthy blood stem cells from a donor to replace the diseased and damaged bone marrow.  A donor may be a family member, an acquaintance or someone who is unrelated. The stem cells in this case, can be collected from the donor's blood or bone marrow within a donor's hipbone as well as from a donated umbilical cord.

Here it is important to note that before undergoing an Allogenic stem cell transplant, a high dosage of chemotherapy or radiation is incorporated to destroy the diseased cells and prepare the body for the donor cells.

Why You May Need An Allogenic Transplant?

An allogenic stem cell transplant is used to treat the following disorders:

  • Acute leukemia
  • Adrenoleukodystrophy
  • Aplastic anemia
  • Bone marrow failure syndromes
  • Chronic leukemia
  • Hemoglobinopathies
  • Hodgkin's lymphoma
  • Immune deficiencies
  • Inborn errors of metabolism
  • Multiple myeloma
  • Myelodysplastic syndromes
  • Neuroblastoma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders
  • POEMS syndrome
  • Primary amyloidosis

Umbilical Cord Blood Transplants: Umbilical Cord contains the cord blood and placenta of a newborn child. It can be collected and frozen for later use. Cord blood contains haematopoietic stem which can produce different cells such as red blood cells, white blood cells and platelets. They are responsible for maintaining blood production in the body and have been used for many years in bone marrow transplants to treat blood diseases such as Leukemia.

Cord blood cells are also immunologically sound as they have not been exposed to infections. This makes them more tolerant against a tissue mismatch between the cord cells and the patient. Thus, they can be used to transplant patients who do not have a fully matched available donor as well.

Haploidentical Transplants: Haploidentical transplants can often be performed more than traditional unrelated donor transplants. Relatives may be eligible to make a donation on a short notice, which may be less likely for unrelated donors.

For donors and patients alike, the procedure for a Haploidentical transplant is much the same as for a standard Allogenic transplant. However, the main difference is that in this type of transplant, patients receive high dosage of chemotherapy days after the transplant. Success rates for Haploidentical transplants are similar to those for conventional transplants.

Frequently Asked Questions

Frequently Asked Questions Currently Not Available

Range of Treatment Cost

15000 - 35000 USD

Top Hospitals

Rating :

NABHNABLJCI

Bone Marrow Transplantation
Indraprastha Apollo Hospital, Delhi

Indraprastha Apollo Hospitals, New Delhi is a multi-specialty tertiary acute care hospital with 710 beds and one of the most sought after destinations in Asia for healthcare. A state-of-the art modern facility in the heart of the capital, it is spread over 15 acres.....

Rating :

NABHNABLJCI

Bone Marrow Transplantation
Medanta -The Medicity

Medanta - the Medicity is one of India's largest multi-super specialty institutes located in Gurgaon, a bustling town in the National Capital Region. Founded by eminent cardiac.....

Rating :

NABHNABL

Bone Marrow Transplantation
BLK Super Speciality Hospital

BLK Super Speciality Hospital has a unique combination of the best in class technology, put to use by the best names in the professional circles to ensure world-class health care to all patients. Spread on five acres of land, with a capacity of 650 beds, BLK Super .....

Rating :

NABHJCI

Bone Marrow Transplantation
Fortis Memorial Research Institute

Fortis Memorial Research Institute (FMRI) is a multi-super-speciality, quaternary care hospital with an enviable international faculty, reputed clinicians, including super-sub-specialists and speciality nurses, supported by cutting&nda.....

Rating :

NABHJCI

Bone Marrow Transplantation
Artemis Hospital

Artemis Hospital, established in 2007, spread across 9 acres, is a 380 bed; state-of-the-art multi-speciality hospital located in Gurgaon, India. Artemis Hospital is the first JCI and NABH accredited hospital in Gurgaon. Desi.....

Rating :

NABHNABL

Bone Marrow Transplantation
Narayana Institute Of Cardiac Sciences

Narayana Institute of Cardiac Sciences is a JCI and NABH accredited heart hospital situated in NH Health city Bangalore. This superspeciality flagship cardiac hospital of Narayana Health is one of the largest in the world and is equi.....

Rating :

NABH

Bone Marrow Transplantation
Jaypee Hospital

The Jaypee Hospital was conceptualized by our revered Founder Chairman, Shri Jai Prakash Gaur with the vision of promoting world-class healthcare amongst the masses by providing quality and affordable medical care with commitment. Jaypee Hospital at Noida is the flagship hospital of the Jaypee.....

Rating :

Bone Marrow Transplantation
Dr. Agarwal's Eye Hospital,Bengaluru

Dr. Agarwal’s Group of Eye Hospitals is extending world class comprehensive eye care services since 59 years with a network of 67 eye hospitals, having global presence. Founded in 1957, our network of eye hospitals is spread across 8 states of India (includin.....

Rating :

Bone Marrow Transplantation
KIMS HOSPITAL

KIMS Asia’s leading tertiary care hospitals is a landmark in healthcare destination in Trivandrum, Kerala, India initiated by KIMS Healthcare Management Ltd, which started in the year 2002 with its flags.....

Rating :

Bone Marrow Transplantation
Nova IVI Fertility

Nova IVI Fertility (NIF) is the among the largest service providers in Fertility Space. NIF aims to bring advanced Assisted Reproductive Technology (ART) to India in partnership with IVI of Spain. The partnership has resulted in a substantial addition to Nova's.....

Top Doctors

Patient Stories

Request A Quote

BONE MARROW TRANSPLANT

A bone marrow transplant is done to replace damaged bone marrow that may have been caused due to disease, infection or chemotherapy. Here, blood stem cells are transplanted which travel to the bone marrow where they promote growth of new bone marrow by producing new blood cells. Bone marrow is responsible to create red blood cells, white blood cells, platelets, etc.

 

Causes of damaged Bone Marrow:

  • Aplastic anemia where bone marrow stops making new blood cells
  • Leukemia, Lymphoma and Multiple myeloma
  • Damaged bone marrow from chemotherapy
  • Congenital Neutropenia is a disorder causing recurring infections
  • Sickle cell anemia
  • Thalassemia

Types of Bone Marrow Transplant

Autologous Transplants: This procedure involves the use of a person’s own stem cells, wherein, the cells are harvested, frozen and stored, then infused back into the patient after intensive therapy. Once the treatment is completed, the cells are returned to the body. However, this technique is rarely used but reduces some serious complications.

The procedure typically takes about an hour. The stem cells after entering the bloodstream, travel to the bone marrow and begin to produce new blood cells, and this process is referred to as ‘Engraftment’.

Using cells from the person’s own body during your stem cell transplant offers advantages over receiving stem cells from a donor such as cases of incompatibility between the donor's cells and recipient’s cells do not occur in cases of an autologous stem cell transplant.

 

Why You May Need An Autologous Transplant?

An autologous stem cell transplant is used to treat the following disorders:

  • Hodgkin's lymphoma
  • Myeloma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders

 

Allogenic Transplants: This procedure involves the usage of cells from a donor and here the donor must be a close genetic match to the recipient. Infact, the success rate is dependent on how close the match is.

An Allogenic stem cell transplant uses healthy blood stem cells from a donor to replace the diseased and damaged bone marrow.  A donor may be a family member, an acquaintance or someone who is unrelated. The stem cells in this case, can be collected from the donor's blood or bone marrow within a donor's hipbone as well as from a donated umbilical cord.

Here it is important to note that before undergoing an Allogenic stem cell transplant, a high dosage of chemotherapy or radiation is incorporated to destroy the diseased cells and prepare the body for the donor cells.

Why You May Need An Allogenic Transplant?

An allogenic stem cell transplant is used to treat the following disorders:

  • Acute leukemia
  • Adrenoleukodystrophy
  • Aplastic anemia
  • Bone marrow failure syndromes
  • Chronic leukemia
  • Hemoglobinopathies
  • Hodgkin's lymphoma
  • Immune deficiencies
  • Inborn errors of metabolism
  • Multiple myeloma
  • Myelodysplastic syndromes
  • Neuroblastoma
  • Non-Hodgkin's lymphoma
  • Plasma cell disorders
  • POEMS syndrome
  • Primary amyloidosis

Umbilical Cord Blood Transplants: Umbilical Cord contains the cord blood and placenta of a newborn child. It can be collected and frozen for later use. Cord blood contains haematopoietic stem which can produce different cells such as red blood cells, white blood cells and platelets. They are responsible for maintaining blood production in the body and have been used for many years in bone marrow transplants to treat blood diseases such as Leukemia.

Cord blood cells are also immunologically sound as they have not been exposed to infections. This makes them more tolerant against a tissue mismatch between the cord cells and the patient. Thus, they can be used to transplant patients who do not have a fully matched available donor as well.

Haploidentical Transplants: Haploidentical transplants can often be performed more than traditional unrelated donor transplants. Relatives may be eligible to make a donation on a short notice, which may be less likely for unrelated donors.

For donors and patients alike, the procedure for a Haploidentical transplant is much the same as for a standard Allogenic transplant. However, the main difference is that in this type of transplant, patients receive high dosage of chemotherapy days after the transplant. Success rates for Haploidentical transplants are similar to those for conventional transplants.

Frequently Asked Questions Currently Not Available
15000 - 35000 USD

Top Hospitals

Rating :

NABHNABLJCI

Open Heart Surgery - Cabg
Indraprastha Apollo Hospital, Delhi

Indraprastha Apollo Hospitals, New Delhi is a multi-specialty tertiary acute care hospital with 710 beds and one of the most sought after destinations in Asia for healthcare. A state-of-the art modern facility in the heart of the capital, it is spread over 15 acres.....

Rating :

NABHNABLJCI

Avr/ Mvr
Medanta -The Medicity

Medanta - the Medicity is one of India's largest multi-super specialty institutes located in Gurgaon, a bustling town in the National Capital Region. Founded by eminent cardiac.....

Rating :

NABHNABL

ASD/ VSD
BLK Super Speciality Hospital

BLK Super Speciality Hospital has a unique combination of the best in class technology, put to use by the best names in the professional circles to ensure world-class health care to all patients. Spread on five acres of land, with a capacity of 650 beds, BLK Super .....

Rating :

NABHJCI

Dilation & Curettage ( D& C)
Fortis Memorial Research Institute

Fortis Memorial Research Institute (FMRI) is a multi-super-speciality, quaternary care hospital with an enviable international faculty, reputed clinicians, including super-sub-specialists and speciality nurses, supported by cutting&nda.....

Rating :

NABHJCI

Bone Marrow Transplanation
Artemis Hospital

Artemis Hospital, established in 2007, spread across 9 acres, is a 380 bed; state-of-the-art multi-speciality hospital located in Gurgaon, India. Artemis Hospital is the first JCI and NABH accredited hospital in Gurgaon. Desi.....

Rating :

NABHNABL

Angioplasty
Narayana Institute Of Cardiac Sciences

Narayana Institute of Cardiac Sciences is a JCI and NABH accredited heart hospital situated in NH Health city Bangalore. This superspeciality flagship cardiac hospital of Narayana Health is one of the largest in the world and is equi.....

Rating :

NABH

Pcnl
Jaypee Hospital

The Jaypee Hospital was conceptualized by our revered Founder Chairman, Shri Jai Prakash Gaur with the vision of promoting world-class healthcare amongst the masses by providing quality and affordable medical care with commitment. Jaypee Hospital at Noida is the flagship hospital of the Jaypee.....

Rating :

Cataract Surgery
Dr. Agarwal's Eye Hospital,Bengaluru

Dr. Agarwal’s Group of Eye Hospitals is extending world class comprehensive eye care services since 59 years with a network of 67 eye hospitals, having global presence. Founded in 1957, our network of eye hospitals is spread across 8 states of India (includin.....

Rating :

Cabg With Avr
KIMS HOSPITAL

KIMS Asia’s leading tertiary care hospitals is a landmark in healthcare destination in Trivandrum, Kerala, India initiated by KIMS Healthcare Management Ltd, which started in the year 2002 with its flags.....

Rating :

Ivf
Nova IVI Fertility

Nova IVI Fertility (NIF) is the among the largest service providers in Fertility Space. NIF aims to bring advanced Assisted Reproductive Technology (ART) to India in partnership with IVI of Spain. The partnership has resulted in a substantial addition to Nova's.....

Top Doctors

Patient Stories

Request A Quote


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